Sumatriptan Injection USP
Autoinjector System
6 mg/0.5 mL
For Subcutaneous Use

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Sumatriptan Injection USP is a prescription medicine used to treat acute migraine headaches with or without aura and acute cluster headaches in adults.


  • Sumatriptan can cause serious side effects such as death, heart attack, stroke, increased high blood pressure, fast heartbeat, changes in mental status like hallucination, agitation and coma, tight muscles or trouble walking, changes in the color or feelings of fingers or toes, decreased blood flow to arms, legs or intestines.
  • Do not take sumatriptan if you have heart disease or a history of heart disease, narrowing of blood vessels in the arms, legs stomach or kidney, uncontrolled high blood pressure, migraines that cause temporary paralysis on one side of the body or Basilar migraine, had a stroke or transient ischemic attack or other issues with blood circulation.
  • Do not take sumatriptan if you have taken another triptan or ergotamine medication in the last 24 hours or are allergic to sumatriptan or its ingredients.
  • Especially tell your healthcare provider if you take antidepressant medicines called:
    • - selective serotonin reuptake inhibitors (SSRIs)
    • - serotonin norepinephrine reuptake inhibitors (SNRIs)
    • - tricyclic antidepressants (TCAs)
    • - monoamine oxidase inhibitors (MAOIs)
  • The most common side effects of sumatriptan injection include: pain or redness at your injection site; tingling or numbness in your fingers or toes; dizziness; warm, hot, burning feeling to your face (flushing); discomfort or stiffness in your neck, feeling weak, drowsy, or tired.